PRODUCT: DRAQ5 Application Area: Live-cell fluorescence microscopy Ease of Use: ⭐⭐⭐⭐⭐ After Sales Service: ⭐⭐⭐⭐⭐ Value for Money: ⭐⭐⭐⭐⭐Average rating: 5.0 Comments: In our work using live-cell confocal fluorescence microscopy, DRAQ5 was used as a nuclear […]
PRODUCT: DRAQ5 Application Area: Immunofluorescence microscopy Ease of Use: ⭐⭐⭐⭐ After Sales Service: not required Value for Money: ⭐⭐⭐Average rating: 3.5 Comments: DRAQ5 was used to label the nuclei because the 405 nm channel was occupied […]
PRODUCT: DRAQ7 Application Area: Flow Cytometry Ease of Use: ⭐⭐⭐⭐⭐ After Sales Service: Not required Value for Money: ⭐⭐⭐Average rating: 4.0 Comments: Works perfect for flow cytometry. Name: Jaromír Vašíček Organisation: NPPC-RIAP Nitra, Slovensko ………………………………….. Manufacturer’s response: Dear Jaromir, thank […]
Is this the breakthrough in treatment of glioblastoma that has been evading us now for decades? Despite very good and well-justified efforts to challenge, for example, 3-D cultures of patient-derived tumor stem cells with the battalion of approved drugs used in cancer therapy nothing has worked. The debate has raged.. Is it the failure to […]
PRODUCT: DRAQ5 Application Area: Immunofluorescence microscopy Ease of Use: ⭐⭐⭐⭐⭐ After Sales Service: ⭐⭐⭐⭐⭐ Value for Money: ⭐⭐⭐⭐⭐Average rating: 5.0 Comments: I’ve been really pleased with DRAQ5 and have found it both reliable and easy to […]
Exciting research published recently in the journal Science sheds new and important light on the presence of cell-free DNA (cfDNA) in the circulation as a potential aid to diagnosis for malignant disease. Led by Prof. Bethan Psaila, University of Oxford, the multi-centre team describe the significant presence of cfDNA sequestered in platelets using microscopy and […]
A gut-on-chip model that generates human intestinal tubules has been used to demonstrate the detectable effect of cytokine exposure, an effect of inflammation in vivo, that causes complex changes in the intestinal epithelial barrier. This cytokine-induced barrier dysfunction was measured by TEER (trans-epithelial electrical resistance), combined compromised cell health (DRAQ7) and cytoskeleton changes (actin) and by lipid […]
A team at IGM Biosciences Inc., led by Kevin Hart and Bruce Keyt demonstrate the improved performance of an engineered IgM anti-CD20 antibody to achieve complement-dependent cytotoxic cell killing for B-cell lymphoma over IgG alternatives. Due to the development of resistance to the traditional IgG-based therapies such novel antibody alternatives are required. The IgM gives better […]
A team at the Univ of Cologne, led by Manolis Pasparakis, sheds new light on the complexity of RIPK1 and its downstream regulation of cell death and inflammation. This is shown in the context of dermal inflammation and the dysregulatory effects of mutations at the sites of autophosphorylation and how these sites contribute to the […]
PRODUCT: DRAQ5 Application Area: Immunofluorescence microscopy Ease of Use: ⭐⭐⭐⭐⭐ After Sales Service: Not required Value for Money: ⭐⭐⭐⭐Average rating: 4.5 Comments: DRAQ5 was used for live imaging of tumor tissue or cells with confocal […]