Hypoxia
The role of hypoxia on cancer and stem cell behaviour is an expanding area of research presenting a renewed focus for drug and biomarker development.
Low oxygen stress conditions can change the biological behaviour and pharmaco-dynamic responses of tumour cells due to the hypoxia-induced activation of cell protective and proliferation mechanisms.
HypoxiTRAK™ is a novel biomarker ideal for use in imaging to report:
- the degree of hypoxic experience of cells
- identify the functionally hypoxic fraction of cells within in a population.
The far red fluorescent HypoxiTRAK™ molecular probe is designed to convert exclusively in hypoxic cells to a bioactive metabolite that retains the parent molecule fluorophore but which now accumulates in cells to provide a positive and persistent far red fluorescent signature.
Related BioStatus Products for Imaging-Based Hypoxia Assays
HypoxiTRAK™ in Imaging-Based Hypoxia Assays
Novel reporter of cellular hypoxic experience.
HypoxiTRAK™ is a novel biomarker ideal for use in flow cytometry to report:
- the degree of hypoxic experience of cells
- identify the functionally hypoxic fraction of cells within in a population.
The far red fluorescent HypoxiTRAK™ molecular probe is designed to convert exclusively in hypoxic cells to a bioactive metabolite that retains the parent molecule fluorophore but which now accumulates in cells to provide a positive and persistent far red fluorescent signature.
Related BioStatus Products for Flow Cytometry-Based Hypoxia Assays
HypoxiTRAK™ in Flow Cytometry-Based Hypoxia Assays
Novel reporter of cellular hypoxic experience.