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Success Stories
BioStatus products are used around the world by scientists like you delighted with the results and how easy they are to achieve. Here are a few examples, backed by the thousands of citations in leading journals.
"DRAQ5™ achieves a GOLD Seal of Quality from independent Customer Reviews"
DRAQ5™ is the only reagent to be recognised in the Platinum, Gold or Silver rankings amongst the tens of thousands of products listed at SelectScience.net.
Background
SelectScience® has announced the first recipients of the new SelectScience® Seal of Quality program, recognising products that have consistently received the highest independent review ratings. The review process has been designed to assist scientists in making important purchasing decisions. The new Seals are assigned to approximately 0.1 % of products on the SelectScience® website and are allocated in line with strict criteria based on the quantity of reviews a product has received and the average rating of those reviews. There are four levels of Seals: Platinum, Gold, Silver, Bronze.
Result
DRAQ5™ is the only reagent to be recognised in the Platinum, Gold or Silver rankings amongst the tens of thousands of products listed at SelectScience.net. It was awarded a GOLD Seal of Quality, reflecting the satisfaction of scientists around the world who chose DRAQ5™ for their research.
Product
DRAQ5™
Press Release
"DRAQ7™ has allowed us to obtain several data sets which we hope to submit to high impact journals, one of which has already been accepted."
Matthew Ware, PhD student Swansea University / Houston Methodist Research Institute
Background / Problem
Common dose-response assays involve fixing different cell populations at a set number of time points to measure the response, for instance, at 3, 6, 12, and 24h of particle exposure. With DRAQ7™ we are able to measure the response every hour for 72h and because the measurements are taken from the same population of cells over time the results are not skewed by variations in cell population susceptibility to the drug. When used in combination with toxic QD we are able to achieve results which show particle dose over time and cellular response over time within the same system simultaneously.
Result / Solution
Our Cytometry group from the Engineering Department in Swansea University have relied on DRAQ7™ to perform live cell imaging in our work in collaboration with the Houston Methodist Research Institute, Houston. DRAQ7™ is easy to use, is non toxic and the signal remains stable for at least 72h (all our experiments ended at this time point). DRAQ7™ has allowed us to obtain several data sets which we hope to submit to high impact journals, one of which has already been accepted - Margulis-Goshen, K., et al., Active curcumin nanoparticles formed from a volatile microemulsion template. Journal of Materials Chemistry B, 2014.
Product used
DRAQ7™
"DRAQ5™ - the go-to stain for DNA"
Richard Cole PhD, Resarch Assistant Professor, Department Biomedical Science, SUNY, USA
Background / Problem
Needed a far-red fluorescent DNA stain that was broad spectrum in terms of cell types and worked with both live and fixed cells.
Result / Solution
DRAQ5™ has proven to be very versatile across many cell types and additionally, is excitable by a number of common laser lines and filters.
It’s high photo-stability combined with ability to stain both live/dead cells make it “go-to” stain for DNA.
Product used
DRAQ5™
"CyGEL™ - suitable for complete immobilisation of LIVE protozoan parasites"
Helen Price PhD, Lecturer, School Life Sciences, Keele University, UK
Background / Problem
The protozoan parasites Leishmania major and Trypanosoma brucei are causative agents of leishmaniasis and African trypanosomiasis, respectively. Live imaging of these organisms is hampered by the rapid flagellum-driven motility of these species.
Result / Solution
We found that CyGEL™ was suitable for complete immobilisation of procyclic stage L. major and T. brucei for 90 minutes without affecting cell viability. This has enabled us to analyse a GFP-tagged form of the L. major membrane-associated protein, HASPB, using live confocal imaging and FRAP.
Reference(s): Price et al, 2010, Molec Biochem Parasitol.; Maclean et al 2012, Cell Micro.
Product used
CyGEL™
"DRAQ5™ is our preferred live cell nuclear stain"
Claire Brown PhD, Director, Advanced BioImaging Facility, McGill University, Canada
Background / Problem
Need a reliable live cell nuclear dye.
Result / Solution
DRAQ5™ is a valuable live cell reagent that is easy to use. It is our preferred live cell nuclear stain because the low intensity, low energy red excitation light it is gentle on living samples.
Preliminary data in our lab also showed improved cell health and higher migration speeds when comparing DRAQ5™ versus Hoechst as a live cell nuclear dye.
Product used
DRAQ5™
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