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CNIO images Pathway

DRAQ7™ NEW!! spectral profile

A new live-cell impermeant, far-red emitting DNA dye ..

The graphs below show standard absorbance and fluorescence emission spectra for DRAQ7 in aqueous solution for a range of different excitation wavelengths. As can be seen, DRAQ7 can be effectively excited by 488nm systems. In these circumstances, we recommend that a long band pass filter be used - to capture as many emitted photons as possible.

Excitation:

633 & 647 nm line optimal (Exλmax 599/644 nm)

488, 514 and 568 lines, sub-optimal (only by flow cytometry)

DRAQ7 abs profile

Emission:

>665 nm to infra-red >800 nm (Emλmax 678 nm / 694 nm intercalated with dsDNA)

Minimal overlap with vis range e.g. GFP and FITC

Emission filters may include 695LP, 715LP or 780 LP

 DRAQ7 em profile

Multi-wavelength imaging with UV / vis fluorochromes

No fluorescence enhance-ment upon DNA binding

Low photobleaching effect

Compatible with optics of flow, laser scanning cytometers and confocal and lamp-based fluorescence microscopes